PT-141 and Erectile Dysfunction

PT-141 and Erectile Dysfunction

PT-141 is a peptide developed based on the Melanotan 2, which is known to be a synthetically produced variant of a peptide hormone.

This is naturally produced in the body and stimulates melanogenesis, also known as the alpha-melanocyte-stimulating hormone. PT-141 does not act on your vascular system, but increases your sexual desire through the nervous system. PT-141 uses a different pathway than medications like Viagra so PT-141 can work when other erectile dysfunction medication have not been successful.

During initial tests, the discovery that Melanotan II caused sexual arousal and erections as side effects was accidental. These effects occurred in nine out of ten male volunteers in a study conducted at the University of Arizona by Dr. Hunter Wells. Additional research found the hormone acts on the nervous system rather than regulating arousal through the vascular system like medications such as Viagra and Cialis.

What is RU58841?

RU58841 is a non-steroidal anti-androgenic medication that was initially developed in the 1980s as a topical treatment remedy for acne and male pattern baldness – androgenetic alopecia.

RU58841 goes by several names. It is also known as PSK3841 or HMR3841. It was renamed after newer companies bought the rights to the original product, RU58841.

The concept of RU58841 is quite old. The idea to develop it was first put forth by a French pharmaceutical company called Roussel Uclaf, way back in the 1970s. Although it had been produced in the 80s, most of the research about its development progressed into the 90s.

The main aim of these scientists was to develop a potent medication that would effectively manage acne and androgenic alopecia when applied topically while avoiding/limiting systemic side effects that are commonly observed with other anti-androgens.

Rats and hamsters were the animal models used to test its effectiveness. During the trial phase of the mediation, the RU58841 results were very promising.

Actually, even small doses as low as 0.001 milligrams showed significant local effects. Even at high doses of up to 0.01 milligrams, the action was still limited to the site of application – a much-desired relief for the researchers.


Oxiracetam is one of the racetams, and is structurally different from piracetam due to a single hydroxyl group. It is also used for nootropic purposes such as enhancing learning in students or preventing against cognitive decline. Like all other racetams, it is a synthetic molecule that is not found in food sources or in nature.

When looking at the evidence for oxiracetam at this point in time it seems to have a fair bit of human evidence for reducing the rate of organic cognitive decline (a natural loss in cognition that occurs during the aging process that is not associated with any disease state) and with dementia, yet the lone study in persons with Alzheimer’s showed no apparent benefit with oxiracetam supplementation. When it does aid in cognitive decline, it is somewhat comparable in potency to Alpha-GPC and seems to be slightly more potent than piracetam.

There is currently no evidence to support cognitive enhancement of oxiracetam in young humans with no cognitive impairment looking to increase memory formation.

When looking at animal evidence, oxiracetam appears to very reliably and potently prevent amnesia induced by a variety of anti-cholinergic or anti-glutaminergic compounds (injections of 3-30mg/kg in rats pretty much normalizing memory formation). It has been implicated in increasing memory formation in otherwise healthy and young rats/mice with no apparent cognitive impairment (suggesting that it can be used as a nootropic) but it appears to require at least a five day loading period.

What are anabolic steroids?

Anabolic steroids are synthetic hormones that help with the growth and repair of muscle tissue. They imitate the male sex hormone, testosterone.

There are legitimate medical uses for anabolic steroids. Anabolic steroids are also misused. People who illegally use anabolic steroids often do so to increase lean muscle mass, reduce fat and speed up recovery from injury.

Anabolic steroids can take the form of tablets, capsules or injectable liquids, depending on the type of steroid.

Common slang terms for steroids include ‘roids’, ‘gear’ and ‘juice’.

Anabolic steroids are classed as performance and image-enhancing drugs (PIEDs).

What is RAD 140?

In fact, many studies have supported that RAD 140 can ensure same results like those with anabolic steroids, but with less adverse consequences. RAD 140 SARM imitates the androgen functions and works with selection action mechanism found exclusively in the tissues of bones and muscles. In this way, it does not negatively affect the other organs of the body.

The drug is considered safer than anabolic steroids, as it is tissue-selective and binds to androgen receptors only in muscle and bones. As it get binds with the receptors, it activates the process of protein synthesis to ensure the higher and faster growth of muscle mass.

For the sports purposes, it means SARM RAD 140 Testolone prefers to be used instead of anabolic steroids for muscle building and enhancing athletic performance.

Because of its safer working mechanism than anabolic steroids, SARM RAD 140 Testolone has gained great popularity among fans and sports enthusiast within a short time. Though, the SARMs substances are still under investigation and have been recognized legally for human use and consumption.